A case of myelodysplastic syndrome with abnormal megakaryocytes and ins(8;3)(q24;q21q26).

作者信息

Bachy-Delhomme M, Bertheas M F, Jaubert J, Calmard P, Vasselon C, Reynaud J, Brizard C P

机构信息

Department of Hematology-Cytogenetics, Centre Hôpitalier, Saint Priest en Juarez, France.

出版信息

Cancer Genet Cytogenet. 1991 Aug;55(1):31-4. doi: 10.1016/0165-4608(91)90231-i.

We report a 56-year-old male patient with refractory anemia with excess of blasts in transformation (RAEB-T) who had an ins(8;3)(q24;q21q26) as the sole chromosome abnormality in bone marrow (BM) cells. The findings of disturbed thrombocytopoiesis with numerous micromegakaryocytes suggest that it could be a variant of the classic ins(3;3)(q26;q21q26) described in hematologic malignancies with abnormal thrombopoiesis.