Kishimoto Yo, Hirano Shigeru, Kato Naomi, Suehiro Atsushi, Kanemaru Shin-ichi, Ito Juichi
Department of Otolaryngology-Head and Neck Surgery, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan.
Ann Otol Rhinol Laryngol. 2008 Dec;117(12):881-5. doi: 10.1177/000348940811701203.
Venous malformations are benign lesions with thin, fragile mucosa overlying a vascular stroma. Vascular anomalies often manifest as subglottic lesions in infants, but venous malformations in adults are rare in the pharyngolaryngeal region. The treatments include open and endoscopic surgery; intraoperative bleeding is often troublesome. Angiolytic lasers such as the potassium titanyl phosphate (KTP) laser enable photocoagulation for such hemorrhagic lesions without bleeding; we report findings from a series of adult patients.
Seven adults were treated with a KTP laser set at a low power of 1.5 W in continuous mode. Photocoagulation was easily performed for shallow lesions; however, laser irradiation of bulky venous malformations resulted only in surface photocoagulation. In such cases, the crust remaining after photocoagulation was removed, and laser energy was repeatedly delivered until no remnant lesion was seen. An office procedure using flexible endoscopy was performed under topical anesthesia for 1 patient with a limited lesion.
The lesions were well controlled in all cases without major complications. A patient with a large obstructing lesion had a relapse. Because the recurrent lesion is small and the patient does not desire additional treatment at this time, she is being observed carefully.
Photocoagulation using the KTP laser is a feasible and relatively safe treatment for pharyngolaryngeal venous malformations in adults.
静脉畸形是一种良性病变,其血管基质上覆盖着薄而脆弱的黏膜。血管异常在婴儿中常表现为声门下病变,但成人的静脉畸形在咽喉区域较为罕见。治疗方法包括开放手术和内镜手术;术中出血往往很麻烦。诸如磷酸钛钾(KTP)激光等血管消融激光能够对这类出血性病变进行光凝而不出血;我们报告一系列成年患者的治疗结果。
7名成年人接受了连续模式下功率为1.5W的低功率KTP激光治疗。对于浅表病变,光凝操作容易进行;然而,对较大的静脉畸形进行激光照射仅导致表面光凝。在这种情况下,去除光凝后残留的痂皮,并反复输送激光能量,直到看不到残留病变。对1例病变有限的患者在局部麻醉下使用软性内镜进行门诊手术。
所有病例的病变均得到良好控制,无重大并发症。1例有大的阻塞性病变的患者出现复发。由于复发病变较小且患者目前不希望接受进一步治疗,故对其进行密切观察。
使用KTP激光进行光凝是治疗成人咽喉部静脉畸形的一种可行且相对安全的方法。