Otolaryngology Department of the Eye, ENT Hospital of Fudan University, Shanghai, PR China.
Acta Otolaryngol. 2023 May-Jun;143(6):518-523. doi: 10.1080/00016489.2023.2220744. Epub 2023 Jun 19.
No standard potassium titanyl phosphate (KTP) laser treatment strategy is available yet for pharyngolaryngeal hemangioma.
To explore the therapeutic effect of KTP laser, alone or combined with bleomycin injection, for pharyngolaryngeal hemangioma.
This observational study included patients with pharyngolaryngeal hemangioma treated between May 2016 and November 2021: KTP laser under local anesthesia, KTP laser under general anesthesia, or KTP laser combined with bleomycin injection under general anesthesia.
A total of 60 patients were recruited, including 17, 19, and 24 patients with grade 1, 2, and 3 hemangiomas, respectively. A total of 21 patients underwent KTP laser under local anesthesia, 31 underwent KTP laser under general anesthesia, and 8 underwent KTP laser under general anesthesia combined with bleomycin. The cure rates were 100%, 89.5%, and 20.8% for grade 1, 2, and 3 lesions, respectively. The prognosis was significantly different among the grades of hemangioma ( < .001).
KTP laser treatment might be an effective treatment for adult patients with pharyngolaryngeal hemangioma. The size of the hemangioma might be the major factor influencing the prognosis. The method of anesthesia and whether it was combined with bleomycin injection might not affect the prognosis.
目前尚无针对咽喉部血管瘤的标准钾钛宝石（KTP）激光治疗策略。
探讨 KTP 激光单独或联合平阳霉素注射治疗咽喉部血管瘤的疗效。
本观察性研究纳入了 2016 年 5 月至 2021 年 11 月期间接受治疗的咽喉部血管瘤患者：局部麻醉下 KTP 激光治疗、全身麻醉下 KTP 激光治疗、全身麻醉下 KTP 激光联合平阳霉素注射治疗。
共纳入 60 例患者，其中 1 级、2 级和 3 级血管瘤患者分别为 17、19 和 24 例。21 例患者在局部麻醉下接受 KTP 激光治疗，31 例患者在全身麻醉下接受 KTP 激光治疗，8 例患者在全身麻醉下联合平阳霉素接受 KTP 激光治疗。1 级、2 级和 3 级病变的治愈率分别为 100%、89.5%和 20.8%。血管瘤的分级之间的预后有显著差异（<0.001）。
KTP 激光治疗可能是成人咽喉部血管瘤的有效治疗方法。血管瘤的大小可能是影响预后的主要因素。麻醉方法以及是否联合平阳霉素注射并不影响预后。
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