Holm Søren
Cardiff Law School, Cardiff University, Museum Avenue, Cardiff CF10 3XJ, United Kingdom.
Dev World Bioeth. 2008 Aug;8(2):82-8. doi: 10.1111/j.1471-8847.2006.00173.x.
This paper discusses the link between pharmacogenetics and race, and the global justice issues that the introduction of pharmacogenetics in pharmaceutical research and clinical practice will raise. First, it briefly outlines the likely impact of pharmacogenetics on pharmaceutical research and clinical practice within the next five to ten years and then explores the link between pharmacogenetic traits and 'race'. It is shown that any link between apparent race and pharmacogenetics is problematic and that race cannot be used as a proxy for pharmacogenetic knowledge. The final section considers the implications of the development of pharmacogenetics for health care systems in low- and middle-income countries.
本文探讨了药物遗传学与种族之间的联系,以及药物遗传学在药物研究和临床实践中的引入所引发的全球正义问题。首先,简要概述了药物遗传学在未来五到十年内对药物研究和临床实践可能产生的影响,然后探讨了药物遗传特征与“种族”之间的联系。结果表明,表面上的种族与药物遗传学之间的任何联系都是有问题的,种族不能用作药物遗传学知识的替代指标。最后一部分考虑了药物遗传学发展对低收入和中等收入国家医疗保健系统的影响。