Timmermans Job, Zhao Yinghuan, van den Hoven Jeroen
Nanoethics. 2011 Dec;5(3):269-283. doi: 10.1007/s11569-011-0135-x. Epub 2011 Nov 9.
Although applications are being developed and have reached the market, nanopharmacy to date is generally still conceived as an emerging technology. Its concept is ill-defined. Nanopharmacy can also be construed as a converging technology, which combines features of multiple technologies, ranging from nanotechnology to medicine and ICT. It is still debated whether its features give rise to new ethical issues or that issues associated with nanopharma are merely an extension of existing issues in the underlying fields. We argue here that, regardless of the alleged newness of the ethical issues involved, developments occasioned by technological advances affect the roles played by stakeholders in the field of nanopharmacy to such an extent that this calls for a different approach to responsible innovation in this field. Specific features associated with nanopharmacy itself and features introduced to the associated converging technologies- bring about a shift in the roles of stakeholders that call for a different approach to responsibility. We suggest that Value Sensitive Design is a suitable framework to involve stakeholders in addressing moral issues responsibly at an early stage of development of new nanopharmaceuticals.
尽管相关应用正在开发且已推向市场,但迄今为止,纳米药学总体上仍被视为一项新兴技术。其概念尚不明确。纳米药学也可被理解为一种融合技术,它融合了从纳米技术到医学以及信息通信技术等多种技术的特点。纳米药学的特点是否引发了新的伦理问题,或者与纳米药学相关的问题仅仅是基础领域现有问题的延伸,目前仍存在争议。我们在此认为,无论所涉伦理问题是否被宣称具有新颖性,技术进步所引发的发展对纳米药学领域利益相关者所扮演的角色产生了如此大的影响,以至于这需要在该领域对负责任的创新采取不同的方法。与纳米药学本身相关的特定特征以及引入相关融合技术的特征——导致了利益相关者角色的转变,这就需要采取不同的责任处理方法。我们建议,价值敏感设计是一个合适的框架,可让利益相关者在新纳米药物开发的早期阶段就负责任地参与解决道德问题。