Suppr超能文献

伦理与纳米药学:新药的价值敏感设计

Ethics and Nanopharmacy: Value Sensitive Design of New Drugs.

作者信息

Timmermans Job, Zhao Yinghuan, van den Hoven Jeroen

出版信息

Nanoethics. 2011 Dec;5(3):269-283. doi: 10.1007/s11569-011-0135-x. Epub 2011 Nov 9.

Abstract

Although applications are being developed and have reached the market, nanopharmacy to date is generally still conceived as an emerging technology. Its concept is ill-defined. Nanopharmacy can also be construed as a converging technology, which combines features of multiple technologies, ranging from nanotechnology to medicine and ICT. It is still debated whether its features give rise to new ethical issues or that issues associated with nanopharma are merely an extension of existing issues in the underlying fields. We argue here that, regardless of the alleged newness of the ethical issues involved, developments occasioned by technological advances affect the roles played by stakeholders in the field of nanopharmacy to such an extent that this calls for a different approach to responsible innovation in this field. Specific features associated with nanopharmacy itself and features introduced to the associated converging technologies- bring about a shift in the roles of stakeholders that call for a different approach to responsibility. We suggest that Value Sensitive Design is a suitable framework to involve stakeholders in addressing moral issues responsibly at an early stage of development of new nanopharmaceuticals.

摘要

尽管相关应用正在开发且已推向市场,但迄今为止,纳米药学总体上仍被视为一项新兴技术。其概念尚不明确。纳米药学也可被理解为一种融合技术,它融合了从纳米技术到医学以及信息通信技术等多种技术的特点。纳米药学的特点是否引发了新的伦理问题,或者与纳米药学相关的问题仅仅是基础领域现有问题的延伸,目前仍存在争议。我们在此认为,无论所涉伦理问题是否被宣称具有新颖性,技术进步所引发的发展对纳米药学领域利益相关者所扮演的角色产生了如此大的影响,以至于这需要在该领域对负责任的创新采取不同的方法。与纳米药学本身相关的特定特征以及引入相关融合技术的特征——导致了利益相关者角色的转变,这就需要采取不同的责任处理方法。我们建议,价值敏感设计是一个合适的框架,可让利益相关者在新纳米药物开发的早期阶段就负责任地参与解决道德问题。

相似文献

1
Ethics and Nanopharmacy: Value Sensitive Design of New Drugs.伦理与纳米药学:新药的价值敏感设计
Nanoethics. 2011 Dec;5(3):269-283. doi: 10.1007/s11569-011-0135-x. Epub 2011 Nov 9.
7
A Framework for Ethical Research and Innovation.伦理研究与创新框架
Sci Eng Ethics. 2021 Feb 10;27(1):11. doi: 10.1007/s11948-021-00287-9.
10
Is biotechnology the new alchemy?生物技术是新的炼金术吗?
Stud Hist Philos Sci. 2009 Mar;40(1):70-80. doi: 10.1016/j.shpsa.2008.12.004.

引用本文的文献

3
Practices of Responsible Research and Innovation: A Review.负责任的研究与创新实践:综述
Sci Eng Ethics. 2020 Apr;26(2):533-574. doi: 10.1007/s11948-019-00167-3. Epub 2019 Dec 16.

本文引用的文献

1
Nanomedicine in the European Commission policy for nanotechnology.欧盟委员会纳米技术政策中的纳米医学
Nanomedicine. 2011 Oct;7(5):519-20. doi: 10.1016/j.nano.2011.07.003. Epub 2011 Jul 28.
2
How do we develop nanopharmaceuticals under open innovation?如何在开放式创新下开发纳医药?
Nanomedicine. 2011 Aug;7(4):371-5. doi: 10.1016/j.nano.2011.05.015. Epub 2011 Jun 22.
3
Converging Technologies, Shifting Boundaries.融合技术,重塑边界。
Nanoethics. 2009 Dec;3(3):213-216. doi: 10.1007/s11569-009-0075-x. Epub 2009 Dec 3.
7
Outlining ethical issues in nanotechnologies.概述纳米技术中的伦理问题。
Bioethics. 2009 Sep;23(7):394-402. doi: 10.1111/j.1467-8519.2007.00623.x.
8
Pharmacogenetics, race and global injustice.药物遗传学、种族与全球不公。
Dev World Bioeth. 2008 Aug;8(2):82-8. doi: 10.1111/j.1471-8847.2006.00173.x.
9
Emerging nanopharmaceuticals.新兴纳米药物
Nanomedicine. 2008 Dec;4(4):273-82. doi: 10.1016/j.nano.2008.06.002. Epub 2008 Jul 18.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验