通过R显带将MYC基因定位于8q24.12----q24.13带，并通过荧光原位杂交将其定位于fra(8)(q24.11)（FRA8E）的远侧。
Mapping of the MYC gene to band 8q24.12----q24.13 by R-banding and distal to fra(8)(q24.11), FRA8E, by fluorescence in situ hybridization.
作者信息
Takahashi E, Hori T, O'Connell P, Leppert M, White R
机构信息
Division of Genetics, National Institute of Radiological Sciences, Chiba, Japan.
出版信息
Cytogenet Cell Genet. 1991;57(2-3):109-11. doi: 10.1159/000133124.
The MYC gene was mapped to R-banded human prometaphase chromosomes and to chromosomes expressing fra(8)(q24.11) by fluorescence in situ hybridization. By high-resolution banding analysis, the fluorescent signals were localized to R-positive band q24.12----q24.13 of the long arm of chromosome 8. Furthermore, the signals were localized near the middle part, q24.12----q24.13, of the distal portion of fra(8)(q24.11) expression. Thus, the precise localization of MYC was to the subband 8q24.12----q24.13.
通过荧光原位杂交技术，将MYC基因定位到经R显带处理的人类早中期染色体以及表达fra(8)(q24.11)的染色体上。通过高分辨率显带分析，荧光信号定位于8号染色体长臂的R阳性带q24.12----q24.13。此外，信号定位于fra(8)(q24.11)表达的远端部分中间位置附近，即q24.12----q24.13。因此，MYC基因的确切定位是在8q24.12----q24.13亚带。
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