Canadian Field Epidemiology Program, Public Health Agency of Canada, Vancouver, British Columbia.
Can J Infect Dis Med Microbiol. 2008 Jan;19(1):69-71. doi: 10.1155/2008/246468.
Necrotizing fasciitis due to Streptococcus pneumoniae is a rare and grave condition, and only a few cases have been reported. Suggested risk factors include minor trauma, systemic lupus erythematosus, immunosuppression secondary to medication, use of intramuscular anti-inflammatories and alcoholism. A fatal case of pneumococcal necrotizing fasciitis that occurred in a 51-year-old woman with a history of alcohol abuse and oral anti-inflammatory use is presented. Her condition was caused by a multi-etiology outbreak of community-acquired pneumonia, from which S pneumoniae serotype 5 was also isolated. The case description outlines the subtle presentation and rapid clinical progression of this condition. Because serotype 5 antigen is included in the polysaccharide 23-valent pneumococcal vaccine, the present case highlights the importance of pneumococcal immunization programs in Canada.
由肺炎链球菌引起的坏死性筋膜炎是一种罕见且严重的疾病,仅有少数病例报告。建议的危险因素包括轻微创伤、红斑狼疮、药物引起的免疫抑制、肌内抗炎药的使用和酗酒。本文报告了一例发生在一名 51 岁有酗酒和口服抗炎药使用史的女性身上的致命性肺炎链球菌坏死性筋膜炎病例。她的病情是由社区获得性肺炎多病因暴发引起的,从肺炎链球菌血清型 5 中也分离出来。病例描述概述了这种疾病的微妙表现和快速临床进展。由于血清型 5 抗原包含在多糖 23 价肺炎球菌疫苗中,因此本病例强调了在加拿大开展肺炎球菌免疫接种计划的重要性。