脊椎动物化学感应受体基因库的非凡多样性。

Extraordinary diversity of chemosensory receptor gene repertoires among vertebrates.

作者信息

Shi P, Zhang J

机构信息

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences, Arthur-Scheunert-Allee 114-116, 650223, Kunming, China.

出版信息

Results Probl Cell Differ. 2009;47:1-23. doi: 10.1007/400_2008_4.

DOI:10.1007/400_2008_4

PMID:19145414

Abstract

Chemosensation (smell and taste) is important to the survival and reproduction of vertebrates and is mediated by specific bindings of odorants, pheromones, and tastants by chemoreceptors that are encoded by several large gene families. This review summarizes recent comparative genomic and evolutionary studies of vertebrate chemoreceptor genes. It focuses on the remarkable diversity of chemoreceptor gene repertoires in terms of gene number and gene sequence across vertebrates and the evolutionary mechanisms that are responsible for generating this diversity. We argue that the great among-species variation of chemoreceptor gene repertoires is a result of adaptations of individual species to their environments and diets.

摘要

化学感觉（嗅觉和味觉）对脊椎动物的生存和繁殖至关重要，它由化学感受器对气味剂、信息素和味觉剂的特异性结合介导，这些化学感受器由几个大基因家族编码。本综述总结了脊椎动物化学感受器基因最近的比较基因组学和进化研究。它关注脊椎动物化学感受器基因库在基因数量和基因序列方面的显著多样性，以及产生这种多样性的进化机制。我们认为，化学感受器基因库在物种间的巨大差异是各个物种适应其环境和饮食的结果。