变应性鼻炎儿童及青少年的鼻吸气峰流量与临床评分
Nasal peak inspiratory flow and clinical score in children and adolescents with allergic rhinitis.
作者信息
Gomes Daniela de Lima, Camargos Paulo Augusto Moreira, Ibiapina Cássio da Cunha, de Andrade Cláudia Ribeiro
机构信息
Department of Pediatrics, Pediatric Pulmonology Section, Federal University of Minas Gerais, Brazil.
出版信息
Rhinology. 2008 Dec;46(4):276-80.
OBJECTIVE
To assess the correlation between nasal inspiratory peak flow (NIPF) and clinical scoring in patients with allergic rhinitis (AR).
METHODS
A concurrent cohort study was carried out with 52 randomly selected patients aged six to 16 with moderate and severe persistent allergic rhinitis, and followed up for eight weeks. Measurements of NIPF and clinical score for AR were evaluated in a blinded manner. Correlations between NIPF and clinical scoring were obtained from linear regression using the Pearson's correlation coefficient (r). Significance level was p < 0.05.
RESULTS
Moderate but statistically significant correlation between NIPF and clinical scoring was found (r = -0.44; p < or = 0.001) and nasal obstruction alone (r = -0.438; p < or = 0.001) were found.
CONCLUSION
Results confirm data from studies conducted with adult patients that found weak correlation between allergic rhinitis symptoms and objective measurements of nasal obstruction as NIPF. NIPF and the clinical scoring are complementary tools to evaluate AR patients.
目的
评估变应性鼻炎（AR）患者的鼻吸气峰流量（NIPF）与临床评分之间的相关性。
方法
对52例年龄在6至16岁的中重度持续性变应性鼻炎患者进行同期队列研究，并随访8周。以盲法评估NIPF测量值和AR临床评分。使用Pearson相关系数（r）通过线性回归得出NIPF与临床评分之间的相关性。显著性水平为p<0.05。
结果
发现NIPF与临床评分之间存在中度但具有统计学意义的相关性（r=-0.44；p≤0.001），且仅鼻塞与临床评分之间也存在相关性（r=-0.438；p≤0.001）。
结论
结果证实了针对成年患者开展的研究数据，这些研究发现变应性鼻炎症状与作为NIPF的鼻阻塞客观测量值之间存在弱相关性。NIPF和临床评分是评估AR患者的互补工具。
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