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牙源性肿瘤:中国人群 1309 例研究。

Odontogenic tumors: a study of 1309 cases in a Chinese population.

机构信息

Department of Oral Pathology, Peking University School and Hospital of Stomatology, 22 South Zhongguancun Avenue, Haidian District, Beijing, PR China.

出版信息

Oral Oncol. 2009 Aug;45(8):706-11. doi: 10.1016/j.oraloncology.2008.11.001. Epub 2009 Jan 14.

Abstract

To determine the relative frequency of odontogenic tumors (OTs) in a Chinese population, files from the department of oral pathology, Peking University School and Hospital of Stomatology, were systematically reviewed for all OTs during the period 1985-2006. Diagnosis of each case was confirmed according to the WHO histological classification for OTs published in 2005. The relevant clinicopathological data of these OTs were analyzed and compared with those of previous series. The present series represents approximately 3.92% of all pathologic specimens accessioned in our department over the same period of time. Of the 1309 OTs, 94.04% were benign and 5.06% were malignant. The most frequent benign tumor was keratocystic odontogenic tumor (38.73%), followed by ameloblastoma (36.52%) and odontomas (6.11%). The prevalence of the remaining tumors appears to be rare. In conclusion, odontogenic tumors are in general uncommon lesions in this Chinese population. The present study identifies some similarities between our data and the previous studies from Africa and Asia and some differences in comparison to the reports from American and European countries.

摘要

为了确定中国人中牙源性肿瘤(OT)的相对频率,系统地复习了 1985 年至 2006 年期间来自北京大学口腔医学院口腔病理科的文件,所有 OT 都根据 2005 年发布的世界卫生组织(WHO)牙源性肿瘤组织学分类进行诊断。分析了这些 OT 的相关临床病理数据,并与以前的系列进行了比较。本系列代表同一时期在我科登记的所有病理标本的约 3.92%。在 1309 个 OT 中,94.04%为良性,5.06%为恶性。最常见的良性肿瘤是角化囊肿性牙源性肿瘤(38.73%),其次是造釉细胞瘤(36.52%)和牙瘤(6.11%)。其余肿瘤的患病率似乎很少。总之,牙源性肿瘤在中国人中通常是不常见的病变。本研究确定了我们的数据与来自非洲和亚洲的先前研究之间的一些相似之处,以及与来自美国和欧洲国家的报告之间的一些差异。

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