Nashashibi Mary, Farah Amir, Abu El-Naaj Imad, Nashashibi Munir
Pathology, Tzafon Medical Center, Azrieli Faculty of Medicine, Bar Ilan University, Tiberias, ISR.
Surgery, Medical College of Wisconsin, Milwaukee, USA.
Cureus. 2025 Feb 5;17(2):e78556. doi: 10.7759/cureus.78556. eCollection 2025 Feb.
Odontogenic tumors are rare lesions with varied clinical presentations and behaviors. A dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm that can be classified into central (intraosseous) and peripheral (extraosseous) types, with a central DGCT often presenting as a bone-expanding lesion. We report a case of a multimorbid 66-year-old male patient with a central DGCT presenting as a painless, 3 × 5.3 cm expansile mass in the right mandibular body. The patient underwent radiographic and histologic assessment followed by tumor enucleation under local anesthesia, which revealed classic features of the DGCT, including ghost cells, calcifications, and a low proliferation index, consistent with low malignant potential.
牙源性肿瘤是一类少见的病变,临床表现和行为各异。牙本质生成性影细胞瘤(DGCT)是一种罕见的牙源性肿瘤,可分为中心型(骨内型)和外周型(骨外型),中心型DGCT常表现为骨质膨胀性病变。我们报告一例66岁的多病男性患者,其中心型DGCT表现为右下颌体部一个3×5.3 cm大小的无痛性膨胀性肿物。患者接受了影像学和组织学评估,随后在局部麻醉下进行肿瘤摘除术,结果显示该DGCT具有典型特征,包括影细胞、钙化以及低增殖指数,提示其恶性潜能较低。