Augustine T, Brown P W, Davies S D, Summers A M, Wilkie M E
Manchester Institute of Nephrology and Transplantation, Manchester Royal Infirmary, Manchester, UK.
Nephron Clin Pract. 2009;111(2):c149-54; discussion c154. doi: 10.1159/000191214. Epub 2009 Jan 16.
Encapsulating peritoneal sclerosis (EPS) is a rare but serious complication of peritoneal dialysis (PD). This review discusses the current understanding of the aetiology and pathogenesis of EPS, highlighting histological features which differentiate it from simple sclerosis of the peritoneal membrane which develops with time on PD. Diagnostic criteria are presented, including the role of imaging techniques. To date there are no randomised controlled trials to guide therapy; however, surgical techniques are an important treatment option. Collaborative research will be essential if this serious problem facing PD is to be solved.
包裹性腹膜硬化（EPS）是腹膜透析（PD）的一种罕见但严重的并发症。本综述讨论了目前对EPS病因和发病机制的理解，突出了其组织学特征，这些特征将其与PD过程中随时间发展的单纯腹膜硬化区分开来。文中介绍了诊断标准，包括成像技术的作用。迄今为止，尚无随机对照试验来指导治疗；然而，手术技术是一种重要的治疗选择。如果要解决PD面临的这一严重问题，合作研究至关重要。
