Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, BT9 7BL, N Ireland,
J Cell Commun Signal. 2008 Dec;2(3-4):95-100. doi: 10.1007/s12079-009-0036-8. Epub 2009 Jan 21.
The Fifth International Workshop on the CCN Family of Genes was held in Toronto October 18-22, 2008. This bi-annual workshop provides a unique opportunity for the presentation and discussion of cutting edge research in the CCN field. The CCN family members have emerged as extracellular matrix associated proteins which play a crucial role in cardiovascular and skeletal development, fibrosis and cancer. Significant progress has been made in the development of model systems to tease apart the CCN signalling pathways in these systems. Results presented at the conference suggest that targeting these pathways now shows real promise as a therapeutic strategy.
第五届细胞周期素基因家族国际研讨会于 2008 年 10 月 18 日至 22 日在多伦多举行。该两年一度的研讨会为展示和讨论细胞周期素领域的前沿研究提供了独特的机会。细胞周期素家族成员已成为细胞外基质相关蛋白，在心血管和骨骼发育、纤维化和癌症中发挥着关键作用。在开发模型系统以剖析这些系统中的细胞周期素信号通路方面已经取得了重大进展。会议上提交的结果表明，针对这些通路的治疗策略现在显示出真正的前景。
