Ma Zhaoxin, Li Ming
Department of Trigeminal Neuralgia, Yueyang Hospital Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Clin J Pain. 2009 Jan;25(1):44-7. doi: 10.1097/AJP.0b013e31817e138e.
The purpose of this study was to describe and evaluate the contributions of "nerve combing" to trigeminal neuralgia (TN) without vascular compression.
Ten of 96 cases with TN who intended to be treated with microvascular decompression in our clinic had no visible vascular compression intraoperatively. The operative procedure for all 10 patients was nerve combining.
At least 3 years after surgery, 7 of 10 patients were pain-free after nerve combing. One patient had little pain relief. One patient experienced significant partial relief, and the intensity of the residual pain in this patient was not severe enough to require medication. Recurrence occurred in 1 case 18 months postoperatively. Permanent sensory deficits were present in 1 patient.
Minimal trigeminal nerve root trauma via nerve combining technique demonstrated a beneficial impact on TN within this cases series. Further studies should be carried out to explore the possible mechanisms of underlying pain and to assess outcomes with respect to currently available medical and surgical treatment options.
本研究旨在描述和评估“神经梳理”对无血管压迫的三叉神经痛(TN)的作用。
在我们诊所,96例拟行微血管减压术治疗的TN患者中,有10例术中未见明显血管压迫。这10例患者的手术方式均为神经梳理。
术后至少3年,10例患者中有7例经神经梳理后无痛。1例患者疼痛缓解不明显。1例患者有明显部分缓解,且该患者残留疼痛强度不足以需要药物治疗。1例患者术后18个月复发。1例患者出现永久性感觉障碍。
通过神经梳理技术对三叉神经根造成的创伤最小,在该病例系列中对TN显示出有益影响。应进一步开展研究,以探索潜在疼痛的可能机制,并评估与目前可用的药物和手术治疗方案相关的结果。