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后颅窝探查术中三叉神经手术操作诱发的面部带状疱疹感染:一例报告

Facial herpes zoster infection precipitated by surgical manipulation of the trigeminal nerve during exploration of the posterior fossa: a case report.

作者信息

Mansour Nassir, Kaliaperumal Chandrasekaran, Choudhari Kishor A

机构信息

Department of Neurosurgery, Regional Neurosciences Unit, Royal Victoria Hospital, Belfast BT12 6BA, UK.

出版信息

J Med Case Rep. 2009 Sep 16;3:7813. doi: 10.4076/1752-1947-3-7813.

Abstract

INTRODUCTION

We present a case of herpes zoster infection (shingles) precipitated by surgical manipulation of the trigeminal nerve root during an attempted microvascular decompression procedure. The pathogenesis of this phenomenon, as well as the importance and role of prophylactic acyclovir in its management, are discussed.

CASE PRESENTATION

A 54-year-old Caucasian man with a classical long-standing left-sided V2 and V3 division primary trigeminal neuralgia refractory to medical management, underwent posterior fossa exploration for microvascular decompression via a standard retromastoid craniectomy. The patient had immediate and complete relief from pain. Three days after the operation, he developed severely painful vesicles with V2 and V3 dermatomal distribution. Rather than the classical paroxysmal, lancinating type of trigeminal neuralgia, the pain experienced by the patient was of a constant burning nature. A clinical diagnosis of herpes zoster (shingles) was made after smear confirmation from microbiological testing. The patient was commenced on antiviral treatment with acyclovir. His vesicular rash and pain gradually subsided over the next two weeks. He remains asymptomatic one year later.

CONCLUSIONS

Postoperative shingles precipitated by trigeminal nerve manipulation during surgery for trigeminal neuralgia can be a distressing and demoralizing experience for the patient. A careful preoperative history, early recognition, and prompt antiviral therapy is necessary.

摘要

引言

我们报告一例在微血管减压手术中试图处理三叉神经根时引发带状疱疹感染(带状疱疹)的病例。本文讨论了这一现象的发病机制,以及预防性使用阿昔洛韦在其治疗中的重要性和作用。

病例介绍

一名54岁的白种男性,患有典型的长期左侧V2和V3分支原发性三叉神经痛,药物治疗无效,通过标准的乳突后颅骨切除术接受后颅窝微血管减压探查手术。患者术后疼痛立即完全缓解。术后三天,他在V2和V3皮节分布区域出现严重疼痛的水疱。患者所经历的疼痛并非典型的阵发性、刀割样三叉神经痛,而是持续性灼痛。经微生物检测涂片确认后,临床诊断为带状疱疹。患者开始接受阿昔洛韦抗病毒治疗。在接下来的两周内,他的水疱皮疹和疼痛逐渐消退。一年后他仍无症状。

结论

三叉神经痛手术中因三叉神经操作引发的术后带状疱疹,对患者来说可能是一种痛苦且令人沮丧的经历。术前仔细询问病史、早期识别并及时进行抗病毒治疗是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6617/2827157/3d0bf773ce7a/1752-1947-0003-0000007813-1.jpg

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