肺成熟度检测的住院晚期早产轻度子痫前期患者：分娩风险有哪些？
Hospitalized late preterm mild preeclamptic patients with mature lung testing: what are the risks of delivery?
作者信息
Lewis D F, McCann J, Wang Y, Cormier C, Groome L
机构信息
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, Shreveport, LA, USA.
出版信息
J Perinatol. 2009 Jun;29(6):413-5. doi: 10.1038/jp.2008.237. Epub 2009 Jan 22.
OBJECTIVE
To evaluate the risk of elective delivery of hospitalized patients with isolated mild preeclampsia with mature fetal lung profile compared with a cohort of patients who had preeclampsia with indicated delivery matched for gestational age.
STUDY DESIGN
Patients with mild preeclampsia requiring hospitalization between 34 and 37 weeks estimated gestational age were offered amniocentesis for assessment of fetal lung maturity. If fetal lung maturity was documented, patients were offered delivery. These cases were then compared with indicated or spontaneously delivered controls with preeclampsia matched for gestational age.
RESULT
A total of 51 cases were identified and matched with 51 controls. Sixteen case neonates (31.4%) were admitted to neonatal intensive care unit compared with 21 controls (41.2%). Five cases (9.8%) in each group developed respiratory distress syndrome (RDS).
CONCLUSION
Elective delivery of mild preeclampsia with mature lung profiles in the late preterm gestation is not without neonatal risks, including a 10% risk of RDS in this series.
目的
评估与孕周匹配的有指征分娩的子痫前期患者队列相比，具有成熟胎儿肺成熟度特征的孤立性轻度子痫前期住院患者进行择期分娩的风险。
研究设计
对孕周估计在34至37周之间需要住院治疗的轻度子痫前期患者进行羊膜腔穿刺术，以评估胎儿肺成熟度。如果记录到胎儿肺成熟，则为患者提供分娩。然后将这些病例与孕周匹配的有指征或自然分娩的子痫前期对照患者进行比较。
结果
共确定了51例病例，并与51例对照进行匹配。16例病例新生儿（31.4%）入住新生儿重症监护病房，而对照中有21例（41.2%）。每组有5例（9.8%）发生呼吸窘迫综合征（RDS）。
结论
孕晚期轻度子痫前期且胎儿肺成熟情况下的择期分娩并非没有新生儿风险，在本系列中呼吸窘迫综合征的风险为10%。
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