Hitti I F, Glasberg S S, McKenzie C, Meltzer B A
Department of Pathology, LaGuardia Hospital, Forest Hills, New York 11375.
Fertil Steril. 1991 Oct;56(4):778-80. doi: 10.1016/s0015-0282(16)54616-0.
Recurrence of heavy vaginal bleeding and massive necrosis of a uterine leiomyosarcoma are reported in a 41-year-old female who was being treated with GnRH-a for a presumed uterine fibroid. The pathogenic mechanisms of such an event are reviewed and discussed in light of the available literature on the subject of GnRH-a and the treatment of uterine smooth muscle neoplasms.
据报道，一名41岁女性在接受GnRH-a治疗疑似子宫肌瘤时，出现了严重阴道出血复发和子宫平滑肌肉瘤大面积坏死的情况。结合关于GnRH-a和子宫平滑肌肿瘤治疗的现有文献，对这一事件的致病机制进行了回顾和讨论。
