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[黄连素抗动脉粥样硬化机制的研究进展]

[Advance on study in anti-atherosclerosis mechanism of berberine].

作者信息

Wu Min, Wang Jie

机构信息

Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2008 Sep;33(18):2013-6.

Abstract

Coptis chinensis is a traditional Chinese herb that has the effect of clearing heat and drying dampness, purging fire to eliminate toxin. Berberine is the main alkaloid of C. chinensis, and researches showed recently, berberine had the effect of anti-atherosclerosis. This paper has reviewed the mechanism of berberine in anti-atherosclerosis from anti-inflammation, regulating lipid, decompression, reducing blood sugar, and inhibiting vascular smooth muscle cell proliferation.

摘要

黄连是一种具有清热燥湿、泻火解毒功效的传统中药。小檗碱是黄连的主要生物碱,最近的研究表明,小檗碱具有抗动脉粥样硬化的作用。本文从抗炎、调节血脂、降压、降糖以及抑制血管平滑肌细胞增殖等方面综述了小檗碱抗动脉粥样硬化的机制。

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