Department of Angio-Cardio-Neurology, IRCCS Neuromed, 86077 Pozzilli, Italy.
Department of Medicine and Surgery, University of Salerno, 84081 Baronissi, Italy.
Int J Mol Sci. 2020 Nov 18;21(22):8706. doi: 10.3390/ijms21228706.
Cardiovascular diseases (CVDs) such as hypertension, atherosclerosis, myocardial infarction, and diabetes are a significant public health problem worldwide. Although several novel pharmacological treatments to reduce the progression of CVDs have been discovered during the last 20 years, the better way to contain the onset of CVDs remains prevention. In this regard, nutraceuticals seem to own a great potential in maintaining human health, exerting important protective cardiovascular effects. In the last years, there has been increased focus on identifying natural compounds with cardiovascular health-promoting effects and also to characterize the molecular mechanisms involved. Although many review articles have focused on the individual natural compound impact on cardiovascular diseases, the aim of this manuscript was to examine the role of the most studied nutraceuticals, such as resveratrol, cocoa, quercetin, curcumin, brassica, berberine and Spirulina platensis, on different CVDs.
心血管疾病（CVDs）如高血压、动脉粥样硬化、心肌梗死和糖尿病是全球范围内严重的公共卫生问题。尽管在过去的 20 年里发现了几种新型的药物治疗方法来减缓 CVDs 的进展，但预防仍然是控制 CVDs 发病的更好方法。在这方面，营养保健品似乎在维持人类健康方面具有巨大的潜力，发挥着重要的保护心血管作用。在过去的几年中，人们越来越关注寻找具有促进心血管健康作用的天然化合物，并对涉及的分子机制进行了描述。虽然许多综述文章都集中在单个天然化合物对心血管疾病的影响上，但本文的目的是研究最受研究的营养保健品，如白藜芦醇、可可、槲皮素、姜黄素、芸薹属、小檗碱和螺旋藻，对不同 CVDs 的作用。
