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[Progressive studies of paeoniflorin].

作者信息

Sun Li-Rong, Cao Xiong, Hou Feng-Qing, Zhu Xin-Hong, Gao Tian-Ming

机构信息

Department of Neurobiology, Southern Medical University, Guangzhou 510515, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2008 Sep;33(18):2028-32.

PMID:19160776
Abstract

Paeoniflorin is one of the bioactive components of Paeonia lactiflora, a traditional Chinese herbal medicine. It is the main monoterpene glucoside isolated from the P. lactiflora in 1963. Since then, researchers have found that paeoniflorin has multifold pharmacological effects. In this review, based on the recent available papers published in PubMed and National Knowledge Infrastructure Data Base, we present the major current approaches in understanding the detection methodology, pharmacokinetics and pharmacology, and toxicology of paeoniflorin.

摘要

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2
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引用本文的文献

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Paeoniflorin exerts protective effect on radiation-induced hepatic fibrosis in rats via TGF-β1/Smads signaling pathway.芍药苷通过TGF-β1/Smads信号通路对大鼠辐射诱导的肝纤维化发挥保护作用。
Am J Transl Res. 2018 Mar 15;10(3):1012-1021. eCollection 2018.
2
Effect of paeoniflorin on the calcium ion concentration in salivary gland cells using confocal laser scanning microscopy.利用共聚焦激光扫描显微镜观察芍药苷对唾液腺细胞钙离子浓度的影响。
Am J Transl Res. 2016 Sep 15;8(9):3678-3688. eCollection 2016.
3
Paeoniflorin protects HUVECs from AGE-BSA-induced injury via an autophagic pathway by acting on the RAGE.
芍药苷通过作用于晚期糖基化终产物受体(RAGE),经由自噬途径保护人脐静脉内皮细胞(HUVECs)免受晚期糖基化终产物-牛血清白蛋白(AGE-BSA)诱导的损伤。
Int J Clin Exp Pathol. 2015 Jan 1;8(1):53-62. eCollection 2015.