Ebrahimi Farideh, Mikaeili Mohammad, Estrada Edson, Nazeran Homer
Biomedical Engineering Department, Shahed University, Tehran, Iran.
Annu Int Conf IEEE Eng Med Biol Soc. 2008;2008:1151-4. doi: 10.1109/IEMBS.2008.4649365.
Currently in the world there is an alarming number of people who suffer from sleep disorders. A number of biomedical signals, such as EEG, EMG, ECG and EOG are used in sleep labs among others for diagnosis and treatment of sleep related disorders. The usual method for sleep stage classification is visual inspection by a sleep specialist. This is a very time consuming and laborious exercise. Automatic sleep stage classification can facilitate this process. The definition of sleep stages and the sleep literature show that EEG signals are similar in Stage 1 of non-rapid eye movement (NREM) sleep and rapid eye movement (REM) sleep. Therefore, in this work an attempt was made to classify four sleep stages consisting of Awake, Stage 1 + REM, Stage 2 and Slow Wave Stage based on the EEG signal alone. Wavelet packet coefficients and artificial neural networks were deployed for this purpose. Seven all night recordings from Physionet database were used in the study. The results demonstrated that these four sleep stages could be automatically discriminated from each other with a specificity of 94.4 +/- 4.5%, a of sensitivity 84.2+3.9% and an accuracy of 93.0 +/- 4.0%.
目前,世界上患有睡眠障碍的人数惊人。诸如脑电图(EEG)、肌电图(EMG)、心电图(ECG)和眼电图(EOG)等一些生物医学信号在睡眠实验室中被用于诊断和治疗与睡眠相关的疾病。睡眠阶段分类的常用方法是由睡眠专家进行目视检查。这是一项非常耗时费力的工作。自动睡眠阶段分类可以简化这一过程。睡眠阶段的定义和睡眠文献表明,在非快速眼动(NREM)睡眠的第1阶段和快速眼动(REM)睡眠中,脑电图信号相似。因此,在这项工作中,尝试仅基于脑电图信号对清醒、第1阶段+快速眼动、第2阶段和慢波阶段这四个睡眠阶段进行分类。为此部署了小波包系数和人工神经网络。研究中使用了来自Physionet数据库的七份整夜记录。结果表明,这四个睡眠阶段能够相互自动区分,特异性为94.4±4.5%,敏感性为84.2±3.9%,准确率为93.0±4.0%。