Boe Alexander J, McGee Koch Lori L, O'Brien Megan K, Shawen Nicholas, Rogers John A, Lieber Richard L, Reid Kathryn J, Zee Phyllis C, Jayaraman Arun
Max Nader Lab for Rehabilitation Technologies and Outcomes Research, Shirley Ryan AbilityLab, Chicago, IL 60611 USA.
2Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208 USA.
NPJ Digit Med. 2019 Dec 20;2:131. doi: 10.1038/s41746-019-0210-1. eCollection 2019.
Polysomnography (PSG) is the current gold standard in high-resolution sleep monitoring; however, this method is obtrusive, expensive, and time-consuming. Conversely, commercially available wrist monitors such as ActiWatch can monitor sleep for multiple days and at low cost, but often overestimate sleep and cannot differentiate between sleep stages, such as rapid eye movement (REM) and non-REM. Wireless wearable sensors are a promising alternative for their portability and access to high-resolution data for customizable analytics. We present a multimodal sensor system measuring hand acceleration, electrocardiography, and distal skin temperature that outperforms the ActiWatch, detecting wake and sleep with a recall of 74.4% and 90.0%, respectively, as well as wake, non-REM, and REM with recall of 73.3%, 59.0%, and 56.0%, respectively. This approach will enable clinicians and researchers to more easily, accurately, and inexpensively assess long-term sleep patterns, diagnose sleep disorders, and monitor risk factors for disease in both laboratory and home settings.
多导睡眠图(PSG)是当前高分辨率睡眠监测的金标准;然而,这种方法具有侵入性、成本高且耗时。相反,市面上的腕部监测器,如ActiWatch,可以低成本地连续多日监测睡眠,但常常高估睡眠时间,并且无法区分睡眠阶段,如快速眼动(REM)和非快速眼动。无线可穿戴传感器因其便携性以及能够获取用于定制分析的高分辨率数据,成为一种很有前景的替代方案。我们展示了一种多模态传感器系统,该系统可测量手部加速度、心电图和远端皮肤温度,其性能优于ActiWatch,检测清醒和睡眠状态的召回率分别为74.4%和90.0%,检测清醒、非快速眼动和快速眼动状态的召回率分别为73.3%、59.0%和56.0%。这种方法将使临床医生和研究人员能够更轻松、准确且低成本地评估长期睡眠模式,诊断睡眠障碍,并在实验室和家庭环境中监测疾病风险因素。