Krstić M, Sulović V, Marković S, Lazarević B
Glas Srp Akad Nauka Med. 1991(40):63-6.
Chorion frondosum biopsy is a method of antenatal diagnosis based on the chorion villi cell analysis, with the aim of detecting hereditary disorders of chromosomal and genetic origin. The method was applied at the Department of Gynaecology and Obstetrics in women with undesired pregnancy from 8 to 12 weeks. This was the first phase of our investigation. Chorion frondosum samples were taken by Jackson's forceps and "Portex" cannula for transcervical aspiration. The role of ultrasound, as a component part of this method, is pointed out in the paper. Ultrasound was applied in a way not to damage the embryo and its membranes, and to locate chorion frondosum--the site of taking the appropriate chorionic villi. The success of detection of foetal chromosomal constitution in our study was 84%. Chromosomopathy was registered in on case. The foetus had tetraploidy--92, XXYY.
叶状绒毛膜活检是一种基于绒毛膜绒毛细胞分析的产前诊断方法，旨在检测染色体和遗传起源的遗传性疾病。该方法应用于妇科和产科，对怀孕8至12周的意外妊娠妇女进行检测。这是我们研究的第一阶段。叶状绒毛膜样本通过杰克逊钳和“Portex”套管进行经宫颈抽吸采集。本文指出了超声作为该方法组成部分的作用。超声的应用方式是不损伤胚胎及其胎膜，并定位叶状绒毛膜——采集合适绒毛膜绒毛的部位。在我们的研究中，胎儿染色体构成检测的成功率为84%。有一例登记为染色体病。胎儿为四倍体——92，XXYY。
