Turaj Wojciech, Slowik Agnieszka, Wnuk Marcin, Szczudlik Andrzej
Stroke. 2009 Mar;40(3):980-2. doi: 10.1161/STROKEAHA.108.528422. Epub 2009 Jan 22.
We compared the diagnostic evaluation and outcome of ischemic stroke between men and women in large cohort of Polish patients.
Our study included 1488 consecutive patients (755 women and 733 men) with ischemic stroke, treated in a single stroke unit between January 2002 and August 2007. We analyzed demographic factors, major risk factors for stroke, severity of neurological deficit on admission, diagnostic work-up performed during the hospital stay, and outcome on discharge.
Women were older than men (70.9+/-13.7 vs 66.2+/-12.7 years; P<0.001) and had greater neurological deficit on admission (median NIHSS score: 7 [3-13] vs 5 [3-10]; P<0.001). They were also less likely to obtain good recovery on discharge (39.2% vs 49.9%; P<0.001). Carotid ultrasound and echocardiography were performed more often in men (77.2% vs 68.7% and 52.4% vs 46.5%, respectively; P<0.05). Lesser neurological deficit on admission, younger age, and lack of history of myocardial infarction or previous stroke, but not gender, were independent predictors of full diagnostic work-up.
Gender does not influence the adequate diagnostic evaluation of ischemic stroke as an independent factor.
我们在一大群波兰患者中比较了男性和女性缺血性卒中的诊断评估及预后情况。
我们的研究纳入了2002年1月至2007年8月期间在单一卒中单元接受治疗的1488例连续性缺血性卒中患者（755例女性和733例男性）。我们分析了人口统计学因素、卒中的主要危险因素、入院时神经功能缺损的严重程度、住院期间进行的诊断检查以及出院时的预后情况。
女性比男性年龄更大（70.9±13.7岁对66.2±12.7岁；P<0.001），且入院时神经功能缺损更严重（美国国立卫生研究院卒中量表[NIHSS]评分中位数：7[3 - 13]对5[3 - 10]；P<0.001）。她们出院时获得良好恢复的可能性也更低（39.2%对49.9%；P<0.001）。男性接受颈动脉超声和超声心动图检查的频率更高（分别为77.2%对68.7%以及52.4%对46.5%；P<0.05）。入院时神经功能缺损较轻、年龄较小以及无心肌梗死或既往卒中史，但不是性别，是进行全面诊断检查的独立预测因素。
性别作为一个独立因素并不影响缺血性卒中的充分诊断评估。
