[非心源性胸痛与胃食管反流病：病理生理学、诊断方法及治疗策略]
[Non-cardiac chest pain and gastroesophageal reflux disease: pathophysiology, diagnostic methods and therapeutic approach].
作者信息
Karoui Sami, Boubaker Jalel, Filali Azza
机构信息
Service de Gastro-entérologie A, Hôpital la Rabta, Tunis.
出版信息
Tunis Med. 2007 Nov;85(11):909-12.
BACKGROUND
Non cardiac chest pain is a frequent symptom in general population. Gastroesophageal reflux disease is the first cause of chest pain without cardiac etiology.
AIM
This review aimed to determine the specific mechanisms for esophageal-induced chest pain, to evaluate the results of the available methods of diagnosis, and to precise the therapeutic options in these patients.
METHODS
Literature Review
RESULTS
Gastroesophageal reflux disease is the most frequent etiology of "DTPA".The mechanism of pathogeny is complex. After eliminating coronary disease, diagnosis is based on esophagus ph-metry and markers. Therapeutic test with PPI would be an alternative option to ph-metry. Treatment is based on PPI with appropriate dose and duration. Surgical treatment is indicated only for selected patients.
背景
非心源性胸痛是普通人群中的常见症状。胃食管反流病是无心脏病因胸痛的首要原因。
目的
本综述旨在确定食管源性胸痛的具体机制，评估现有诊断方法的结果，并明确这些患者的治疗选择。
方法
文献综述
结果
胃食管反流病是“非心源性胸痛”最常见的病因。发病机制复杂。排除冠心病后，诊断基于食管pH测定和标志物。使用质子泵抑制剂进行治疗性试验是pH测定的替代选择。治疗基于适当剂量和疗程的质子泵抑制剂。手术治疗仅适用于特定患者。
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