Mrad Sonia Mazigh, Boukthir Samir, Gharsallah Lamia, Bouyahia Olfa, Faten Fdhila, Fetni Ihem, Barsaoui Sihem, Zouari Bechir, Samoud Azza
Service de Médecine Infantile C - Hôpital d'Enfants de Tunis.
Tunis Med. 2007 Nov;85(11):930-4.
Helicobacter pylori infection frequency in hematemesis was scarcely studied.
to asses the frequency of this infection in children with upper gastrointestinal bleeding and to study the endoscopic and histological features.
It is a retrospective study including 180 children who underwent an endoscopy for upper gastrointestinal bleeding. Our population was divided in two groups. The group 1 (n=95) has performed gastric biopsy. The group 2 (n=95) has'nt performed gastric biopsy. For each group, we studied the personal and familial history of gastroenterologic disease, the hospital where they come from, the importance of bleeding, the drug intake effecting the gastric mucosa, the endoscopic and histological features.
The helicobacter pylori infection was present in 48% of the children. The mean age of these children was 99.8 +/- 42.1 months versus 95.7 +/- 44 months (p=0.13) The comparison of the two groups according to Hp infection, and the others parameters don't found any differences. All the infected children have chronic gastritis 40/40 versus 13/44 in the non infected children (p>10 -6).
The frequency of Hp infection was high in this group of patients with upper gastrointestinal bleeding. It was probably underestimated because the investigation was not complete. We emphasize that Hp infection has to be investigated and systematically eradicated whenever there were severe symptoms like hematemesis indicating therefore organic disease.
关于呕血患者中幽门螺杆菌感染率的研究极少。
评估上消化道出血儿童中这种感染的发生率，并研究内镜和组织学特征。
这是一项回顾性研究，纳入了180例因上消化道出血接受内镜检查的儿童。我们的研究对象分为两组。第1组（n = 95）进行了胃活检。第2组（n = 95）未进行胃活检。对于每组，我们研究了胃肠疾病的个人和家族史、他们来自的医院、出血的严重程度、影响胃黏膜的药物摄入情况、内镜和组织学特征。
48%的儿童存在幽门螺杆菌感染。这些感染儿童的平均年龄为99.8±42.1个月，未感染儿童为95.7±44个月（p = 0.13）。根据幽门螺杆菌感染情况对两组进行比较，其他参数未发现差异。所有感染儿童均患有慢性胃炎，40/40，未感染儿童为13/44（p>10 -6）。
在这组上消化道出血患者中，幽门螺杆菌感染率很高。由于调查不完整，其感染率可能被低估。我们强调，只要出现像呕血这样提示器质性疾病的严重症状，就必须对幽门螺杆菌感染进行检查并系统根除。
