移民与乙型肝炎病毒：流行病学、临床及治疗方面

Immigration and hepatitis B virus: epidemiological, clinical and therapeutic aspects.

作者信息

Palumbo E, Scotto G, Cibelli D C, Faleo G, Saracin A, Angarano G

机构信息

Clinic of Infectious Diseases, University of Foggia, Foggia, Italy.

出版信息

East Mediterr Health J. 2008 Jul-Aug;14(4):784-90.

PMID:19166160

Abstract

This study in Italy aimed to evaluate the epidemiological, clinical and therapeutic aspects of hepatitis B virus (HBV) infection in a population of recent (< 6 months) immigrants. Between February 2003 and December 2004, 83 (9.3%) out of 890 immigrants tested positive for hepatitis B surface antigen. All were men and 62.6% came-from Africa, 21.6% from Asia and 16.8% from Eastern Europe. About half (54.3%) of the patients had elevated alanine aminotransferase levels and detectable serum HBV DNA. Genotype distribution was as follows: E (20 cases), D (14 cases) and A (11 cases). Our study underscores the potential of migratory flow to introduce genotype non-D hepatitis B virus into our country.

摘要

这项意大利的研究旨在评估近期（<6个月）移民人群中乙型肝炎病毒（HBV）感染的流行病学、临床和治疗方面情况。在2003年2月至2004年12月期间，890名移民中有83人（9.3%）乙型肝炎表面抗原检测呈阳性。所有患者均为男性，62.6%来自非洲，21.6%来自亚洲，16.8%来自东欧。约一半（54.3%）的患者丙氨酸转氨酶水平升高且血清HBV DNA可检测到。基因型分布如下：E型（20例）、D型（14例）和A 型（11例）。我们的研究强调了移民流动可能将非D基因型乙型肝炎病毒引入我国。