Hakawi A M, Al Rabiah F A
Section of Infectious Diseases, Department of Medicine, King Fahad Medical City, Riyadh, Saudi Arabia.
East Mediterr Health J. 2008 Jul-Aug;14(4):966-71.
We aimed to study the clinical pattern of nocardiosis in a tertiary care hospital in Saudi Arabia using a retrospective review of cases from 1987 to 2003. A total of 19 patients were identified as having culture-proven nocardial infection. The most common underlying condition was renal transplantation in 8 patients (42%). Lungs were the most common sites of involvement in 12 patients (63%). Three Nocardia species were isolated in our series: N. asteroides (58%), N. brasiliensis (21%), and N. otitidiscaviarum (21%). A high index of suspicion is essential in susceptible patients presenting with pulmonary infiltrate, cerebral abscess or deep soft-tissue abscess and usually requires an active diagnostic workup and early administration of appropriate therapy.
我们旨在通过回顾性分析沙特阿拉伯一家三级护理医院1987年至2003年的病例，研究诺卡菌病的临床模式。共有19例患者被确诊为经培养证实的诺卡菌感染。最常见的基础疾病是肾移植，共8例（42%）。肺部是最常受累的部位，共12例（63%）。我们的研究系列中分离出三种诺卡菌：星形诺卡菌（58%）、巴西诺卡菌（21%）和豚鼠耳炎诺卡菌（21%）。对于出现肺部浸润、脑脓肿或深部软组织脓肿的易感患者，高度怀疑至关重要，通常需要积极的诊断检查和早期给予适当治疗。
