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肢端肥大症中的N-乙酰-β-葡萄糖苷酶与蛋白尿

N-acetyl-beta-glucosaminidase and albuminuria in acromegaly.

作者信息

Skrha J, Marek J, Srámková J, Stolba P

机构信息

Department of Internal Medicine 3, Faculty of Medicine, Charles University, Prague, Czechoslovakia.

出版信息

Horm Metab Res. 1991 Jun;23(6):285-7.

PMID:1916641
Abstract

Significantly increased albuminuria and N-acetyl-beta-glucosaminidase activity in serum and urine have been observed in acromegalic patients in comparison with healthy persons (P less than 0.001). No relationship between these biochemical variables and serum growth hormone or insulin concentration was found in our group of patients. Significant correlation was determined between urinary NAG activity and albuminuria of acromegalic patients (r = 0.84).

摘要

与健康人相比,肢端肥大症患者血清和尿液中的蛋白尿和N-乙酰-β-葡萄糖苷酶活性显著增加(P<0.001)。在我们的患者组中,未发现这些生化变量与血清生长激素或胰岛素浓度之间存在关联。肢端肥大症患者的尿NAG活性与蛋白尿之间存在显著相关性(r = 0.84)。

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