Paramasivan Rajaiah, Philip Samuel Paulraj, Thenmozhi Velayutham, Rajendran Rathinasamy, Victor Jerald Leo Soosaimanickam, Dhananjeyan Kutty Jagadeeswaran, Krishnamoorthi Ranganathan, Arunachalam Natarajan, Tyagi Brij Kishore
Centre for Research in Medical Entomology, Madurai, India.
Jpn J Infect Dis. 2009 Jan;62(1):67-9.
Virological investigation was carried out to determine the etiology of suspected Chikungunya fever among humans reported in the Lakshadweep islands in the Indian Ocean. Three out of 23 acute sera samples showed cytopathological changes in Vero cell lines. Further, indirect immunofluorescence antibody test and reverse transcriptase-polymerase chain reaction studies demonstrated the Chikungunya virus etiology during the episode. E1 gene sequence analysis has confirmed the involvement of the Central/East African genotype of the Chikungunya virus.
开展了病毒学调查，以确定在印度洋拉克沙群岛报告的疑似基孔肯雅热病例的病因。23份急性血清样本中有3份在Vero细胞系中显示出细胞病理学变化。此外，间接免疫荧光抗体试验和逆转录聚合酶链反应研究证实了此次疫情期间基孔肯雅病毒的病因。E1基因序列分析证实了基孔肯雅病毒的中/东非基因型的参与。
