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[Splenic infarction after warfarin discontinuation during atrial fibrillation].

作者信息

Trappolini M, Scorzai A, Loguercio V, Stoppo M, Sebastianelli A, Iannotta M, Del Porto F, Proietta M, Aliberti G

机构信息

UOC di Medicina Interna, Ospedale S Andrea, II Facoltà di Medicina e Chirurgia, Università di Roma Sapienza, Roma, Italia.

出版信息

Clin Ter. 2008 Nov-Dec;159(6):435-7.

PMID:19169604
Abstract

We describe a case of patient with splenic infarction, admitted to our department for sudden abdominal pain and fever after discontinuation of anticoagulant therapy for atrial fibrillation, complicating a dilated myocardiopathy and mechanical prosthetic valve. Diagnosis of splenic infarction was made by enhanced-contrast computed tomography, while ultrasounds and radiography were negative. Anticoagulant therapy, gold-standard treatment, was followed by fast clinical improvement. Moreover, splenic infarction should be considered in all cases of acute or chronic pain in left hypochondrium and especially in patients with emboligenous cardiopathies or atrial fibrillation, the most common arrhythmia source of peripheral embolism in clinical practice.

摘要

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[Splenic infarction after warfarin discontinuation during atrial fibrillation].
Clin Ter. 2008 Nov-Dec;159(6):435-7.
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Pro: 'Warfarin should be the drug of choice for thromboprophylaxis in elderly patients with atrial fibrillation'. Why warfarin should really be the drug of choice for stroke prevention in elderly patients with atrial fibrillation.正方观点:“华法林应该是老年房颤患者血栓预防的首选药物”。为什么华法林确实应该成为老年房颤患者预防中风的首选药物。
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引用本文的文献

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Catastrophic cerebral antiphospholipid syndrome presenting as cerebral infarction with haemorrhagic transformation after sudden withdrawal of warfarin in a patient with primary antiphospholipid syndrome.原发性抗磷脂综合征患者停用华法林后突发脑梗死伴出血转化,表现为灾难性脑抗磷脂综合征
BMJ Case Rep. 2010;2010. doi: 10.1136/bcr.09.2009.2243. Epub 2010 Jan 13.