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[机械心脏瓣膜患者抗凝治疗暂时中断后的血栓栓塞并发症]

[Thromboembolic complication following temporary discontinuance of anticoagulant therapy in a patient with mechanical heart valve].

作者信息

Christensen Thomas Decker, Houlind Kim C, Klaaborg Kaj Erik, Kure Hans-Henrik O, Eiskjaer Hans, Hasenkam John Michael

机构信息

Arhus Universitetshospital, Skejby Sygehus, Hjerte-, Lunge-, Karkirurgisk Afdeling T og Hjertemedicinsk Afdeling B, og Aarhus Universitet, Institut for Eksperimentel Klinisk Forskning.

出版信息

Ugeskr Laeger. 2003 Jul 7;165(28):2823-4.

PMID:12891906
Abstract

Patients with mechanical heart valves are treated with oral anticoagulant therapy in order to minimize the risk of thromboembolism. During invasive procedures it is recommended to temporarily discontinue the oral anticoagulant therapy and substitute with injections of low-molecular-weight heparin. We describe a case where a patient discontinued the oral anticoagulant therapy and had no substitution with low-molecular-weight heparin. The patient had an embolism to the coronary arteries causing progressive heart failure, and the patient was subsequently heart transplanted.

摘要

患有机械心脏瓣膜的患者接受口服抗凝治疗,以将血栓栓塞风险降至最低。在侵入性操作期间,建议暂时停用口服抗凝治疗,并改用低分子量肝素注射。我们描述了一例患者停用口服抗凝治疗且未用低分子量肝素替代的病例。该患者发生冠状动脉栓塞,导致进行性心力衰竭,随后接受了心脏移植。

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