Capron J, Steichen O
Internal Medicine Dept, Tenon Hospital, Paris University, France.
Infection. 2009 Apr;37(2):179-80. doi: 10.1007/s15010-008-8287-5.
A 97-year-old lady was hospitalized for left leg cellulitis. Comorbidity included hypertension and congestive heart failure. While in hospital, she developed a painless vesicular rash localized to the territory of the left trigeminal nerve (third branch), which evolved to pustules and crusts (Figure 1). A chickenpox-like disseminated eruption of vesicles followed within 4 days, with the same evolution pattern (Figure 2).The diagnosis of disseminated zoster was suspected. A PCR analysis confirmed the presence of varicella-zoster-virus (VZV) in an abdominal vesicle. The patient was treated with oral valacyclovir for 7 days. Clinical examination, laboratory tests (including HIV serology), and a chest radiograph revealed no evidence of underlying immunodeficiency or malignancy.
一位97岁的女性因左腿蜂窝织炎住院。合并症包括高血压和充血性心力衰竭。住院期间,她在左侧三叉神经(第三支)分布区域出现了无痛性水疱疹,随后发展为脓疱和结痂(图1)。4天内出现了类似水痘的水疱播散性皮疹,演变模式相同(图2)。怀疑为播散性带状疱疹。聚合酶链反应(PCR)分析证实腹部水疱中存在水痘-带状疱疹病毒(VZV)。患者接受口服伐昔洛韦治疗7天。临床检查、实验室检查(包括HIV血清学检查)和胸部X线检查均未发现潜在免疫缺陷或恶性肿瘤的证据。