Storch Eric A, Abramowitz Jonathan S, Keeley Mary
Department of Pediatrics, Psychiatry, and Psychology, University of South Florida, Box 7523, 800 6th Street South, St. Petersburg, FL 33701, USA.
Depress Anxiety. 2009;26(9):806-13. doi: 10.1002/da.20481.
This study examined factors associated with obsessive-compulsive disorder (OCD) related functional disability in 87 treatment-seeking adults with OCD.
A trained evaluator administered the Yale-Brown Obsessive-Compulsive Scale and Brown Assessment of Beliefs Scale. Patients completed the Sheehan Disability Scale, Obsessive-Compulsive Inventory-Revised, Interpretation of Intrusions Inventory, Thought-Action Fusion Scale, Beck Depression Inventory Second Edition, and State Trait Anxiety Inventory-Trait Version.
Results indicated that OCD symptoms, anxiety, depression, and the tendency to misinterpret the significance of intrusive thoughts were related to functional disability. Two variables-depressive symptoms and the extent to which a patient attempts to resist and is able to control OCD symptoms-emerged as unique predictors of functional disability. Mediational analyses indicated that both of these variables fully mediated the relationship between OCD-related distress and functional disability.
Results are discussed in terms of predictors of functional disability in OCD and in terms of implications for assessment and treatment.
本研究调查了87名寻求治疗的强迫症成年患者中与强迫症相关功能残疾有关的因素。
一名经过培训的评估人员进行了耶鲁-布朗强迫症量表和布朗信念评估量表的测试。患者完成了希恩残疾量表、强迫症量表修订版、闯入思维解释量表、思维-行动融合量表、贝克抑郁量表第二版和状态-特质焦虑量表-特质版。
结果表明，强迫症症状、焦虑、抑郁以及对闯入性思维意义的错误解读倾向与功能残疾有关。两个变量——抑郁症状以及患者试图抵抗并能够控制强迫症症状的程度——成为功能残疾的独特预测因素。中介分析表明，这两个变量都完全中介了与强迫症相关的痛苦和功能残疾之间的关系。
从强迫症功能残疾的预测因素以及对评估和治疗的影响方面对结果进行了讨论。
