Kehoe E James, Olsen Kirk N, Ludvig Elliot A, Sutton Richard S
School of Psychology, University of New South Wales, Sydney, New South Wales, Australia.
Behav Neurosci. 2009 Feb;123(1):212-7. doi: 10.1037/a0014122.
The present experiment was aimed at characterizing the timing of conditioned nictitating membrane (NM) movements as function of the interstimulus interval (ISI) in delay conditioning for rabbits (Oryctolagus cuniculus). Onset latency and peak latency were approximately, but not strictly, scalar for all but the smallest movements (<.10 mm). That is, both the mean and standard deviation of the timing measures increased in proportion to the ISI, but their coefficients of variation (standard deviation/mean) tended to be larger for shorter ISIs. For all ISIs, the absolute timing of the NM movements covaried with magnitude. The smaller movements (approximately, .11-.50 mm) were highly variable, and their peaks tended to occur well after the time of US delivery. The larger movements (>.50 mm) were less variable, and their peaks were better aligned with the time of US delivery. These results are discussed with respect to their implications for current models of timing in eyeblink conditioning.
本实验旨在确定家兔（穴兔）延迟条件反射中条件性瞬膜（NM）运动的时间安排作为刺激间隔（ISI）的函数。除了最小的运动（<.10毫米）外，起始潜伏期和峰值潜伏期大致但不严格呈标量。也就是说，时间测量的平均值和标准差均与ISI成比例增加，但较短ISI时它们的变异系数（标准差/平均值）往往更大。对于所有ISI，NM运动的绝对时间与幅度共变。较小的运动（约.11-.50毫米）高度可变，其峰值往往在美国投递时间之后很久才出现。较大的运动（>.50毫米）变异性较小，其峰值与美国投递时间更吻合。将结合这些结果对当前眨眼条件反射时间模型的影响进行讨论。
