Goldman Mindy, Xi Guoliang, Yi Qi-Long, Fan Wenli, O'Brien Sheila F
Canadian Blood Services Donor and Transplantation Services, University of Ottawa, Ottawa, Ontario, Canada.
Transfusion. 2009 Apr;49(4):648-54. doi: 10.1111/j.1537-2995.2008.02037.x. Epub 2009 Jan 2.
In August 2005, the Canadian Blood Services decreased the deferral period for tattooing and ear or body piercing from 12 to 6 months. This study assessed the impact of this change on blood safety and availability.
The prevalence of these activities was assessed on an anonymous mail-out survey of 40,000 recent donors. Transmissible disease (TD) marker rates were calculated using the National Epidemiology Donor Database. A case-control study was performed comparing risk factors in TD-positive donors with matched controls. Donor deferral rates were assessed before and after the change in deferral period.
The prevalence rates of tattoo, ear piercing, and body piercing were 13.7, 53.6, and 10.4 percent in survey respondents, respectively, with up to 0.7 percent of activity likely to represent deferrable risk. TD marker rate was low and stable at 21.6 per 100,000 donations before and 19.2 per 100,000 donations after the change in deferral length. Remote tattoo was associated with hepatitis C virus (HCV) risk (odds ratio, 5.43; 95% confidence interval, 1.82-16.2), but neither recent tattoo nor piercing was a risk factor for HCV or hepatitis B virus. Shortening of the deferral period reduced deferrals by 20 percent for tattoo and 32 percent for piercing.
There was no measurable adverse effect on safety and a positive but less than expected effect on blood availability after shortening the deferral period for tattoo and piercing. The length of other temporary deferrals should be reassessed, since their current contribution to blood safety may be negligible.
2005年8月,加拿大血液服务中心将纹身、耳部或身体穿孔后的延期献血期从12个月缩短至6个月。本研究评估了这一变化对血液安全和供应的影响。
通过对40000名近期献血者进行匿名邮寄调查,评估这些行为的流行情况。使用国家流行病学献血者数据库计算可传播疾病(TD)标志物率。进行病例对照研究,比较TD阳性献血者与匹配对照的危险因素。在延期献血期改变前后评估献血者延期率。
在调查对象中,纹身、耳部穿孔和身体穿孔的流行率分别为13.7%、53.6%和10.4%,其中高达0.7%的行为可能代表可延期的风险。TD标志物率较低且稳定,延期期改变前每100000次献血为21.6例,改变后为每100000次献血19.2例。远距离纹身与丙型肝炎病毒(HCV)风险相关(比值比,5.43;95%置信区间,1.82 - 16.2),但近期纹身和穿孔均不是HCV或乙型肝炎病毒的危险因素。缩短延期期使纹身延期率降低了20%,穿孔延期率降低了32%。
缩短纹身和穿孔的延期期后,对安全性没有可测量的不良影响,对血液供应有积极但低于预期的影响。其他临时延期的时长应重新评估,因为它们目前对血液安全的贡献可能微不足道。