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鉴定引发呼吸道过敏的大豆蛋白。

Identification of soybean proteins responsible for respiratory allergies.

作者信息

González R, Zapatero L, Caravaca F, Carreira J

机构信息

Alergia e Inmunología Abelló S.A., Madrid, España.

出版信息

Int Arch Allergy Appl Immunol. 1991;95(1):53-7. doi: 10.1159/000235454.

DOI:10.1159/000235454
PMID:1917110
Abstract

Serum samples from 32 patients who suffered attacks during the asthma outbreaks of 1987 and 1988 in Cartagena, Spain, supposedly caused by soybean dust, were studied. At least 90% had specific IgE to shell components and only 13% showed specific IgE to shell-depleted soybean grains. A control group of 32 patients who also suffered asthma attacks but on different days from those of the outbreaks were negative. The shell's most important allergen with an apparent molecular weight of 8 kDa was not present in shell-depleted grains. This allergen as well as other less important shell allergens may be different from the allergens already identified by using serum from patients suffering food allergy to soya.

摘要

对1987年和1988年西班牙卡塔赫纳哮喘暴发期间发作的32名患者的血清样本进行了研究,这些暴发据推测是由大豆粉尘引起的。至少90%的患者对豆荚成分有特异性IgE,只有13%的患者对去除豆荚的大豆籽粒显示出特异性IgE。另一组32名同样患有哮喘发作但发作时间与暴发时间不同的患者作为对照组,结果为阴性。豆荚中最重要的过敏原,表观分子量为8 kDa,在去除豆荚的籽粒中不存在。这种过敏原以及其他不太重要的豆荚过敏原可能与使用对大豆食物过敏患者的血清已鉴定出的过敏原不同。

相似文献

1
Identification of soybean proteins responsible for respiratory allergies.鉴定引发呼吸道过敏的大豆蛋白。
Int Arch Allergy Appl Immunol. 1991;95(1):53-7. doi: 10.1159/000235454.
2
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