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应激性生活事件在银屑病和慢性荨麻疹诱发或加重中的作用。

Role of stressful life events in induction or exacerbation of psoriasis and chronic urticaria.

作者信息

Malhotra S K, Mehta Vivek

机构信息

Department of Dermatology, Venereology and Leprology, GGS Medical College and Hospital, Faridkot (Punjab), India.

出版信息

Indian J Dermatol Venereol Leprol. 2008 Nov-Dec;74(6):594-9. doi: 10.4103/0378-6323.45100.

DOI:10.4103/0378-6323.45100
PMID:19171981
Abstract

BACKGROUND

The possibility of a causal influence of emotional stress, especially of stressful life events, on the course of various skin diseases has long been postulated. Previous reports addressing its influence on skin psoriasis and chronic urticaria have been mainly anecdotal.

OBJECTIVE

The aim of this study was to evaluate the stressful events of life within 1 year preceding onset or exacerbation of skin disease in patients of psoriasis vulgaris and chronic urticaria.

METHOD

Fifty consecutive clinically diagnosed psoriasis patients and 50 consecutive clinically diagnosed chronic urticaria patients were examined clinically and administered Gurmeet Singh's presumptive stressful life events scale.

RESULTS

Stressful life events were seen in 26% of the patients in the psoriasis vulgaris group and 16% of the patients in the chronic urticaria group within 1 year preceding onset or exacerbation of skin disease. In the psoriasis vulgaris group, the most common stressful life event seen was financial loss or problems (8%), followed by death of close family member (4%), sexual problems (4%), family conflict (2%), major personal illness or injury (2%), and transfer or change in working conditions (2%), failure in examinations (2%), family member unemployed (2%), illness of family member (2%), getting married or engaged (2%), miscellaneous (2%). In the chronic urticaria group, the most common stressful life event seen was death of a close family member (6%), followed by family conflict (2%), financial loss or problems (2%), sexual problems (2%), illness of family member (2%), getting married or engaged (2%), trouble at work with colleagues, superiors, or subordinates (2%), going on a pleasure trip (2%) and extramarital relations (2%).

CONCLUSION

Psychological stress plays a significant role in triggering or exacerbating dermatological diseases. Our study indicates the role of relaxation therapies and stress management programs in chronic diseases such as psoriasis and chronic urticaria. Psychological interventions can help individuals to reinterpret events and develop strategies to cope with stressful events, thus decreasing morbidity due to these diseases.

摘要

背景

长期以来,人们一直假定情绪压力,尤其是应激性生活事件,可能对各种皮肤病的病程产生因果影响。以往关于其对皮肤银屑病和慢性荨麻疹影响的报道主要是 anecdotal。

目的

本研究旨在评估寻常型银屑病和慢性荨麻疹患者在皮肤病发作或加重前1年内的应激性生活事件。

方法

对50例连续临床诊断的银屑病患者和50例连续临床诊断的慢性荨麻疹患者进行临床检查,并使用古尔密特·辛格的推定应激性生活事件量表。

结果

在寻常型银屑病组中,26%的患者在皮肤病发作或加重前1年内经历了应激性生活事件;在慢性荨麻疹组中,这一比例为16%。在寻常型银屑病组中,最常见的应激性生活事件是经济损失或问题(8%),其次是近亲死亡(4%)、性问题(4%)、家庭冲突(2%)、重大个人疾病或伤害(2%)、工作调动或工作条件改变(2%)、考试失败(2%)、家庭成员失业(2%)、家庭成员患病(2%)、结婚或订婚(2%)、其他(2%)。在慢性荨麻疹组中,最常见的应激性生活事件是近亲死亡(6%),其次是家庭冲突(2%)、经济损失或问题(2%)、性问题(2%)、家庭成员患病(2%)、结婚或订婚(2%)、与同事、上级或下级工作中出现问题(2%)、进行愉快旅行(2%)和婚外情(2%)。

结论

心理压力在引发或加重皮肤病方面起着重要作用。我们的研究表明了放松疗法和压力管理计划在银屑病和慢性荨麻疹等慢性病中的作用。心理干预可以帮助个体重新诠释事件,并制定应对应激性生活事件的策略,从而降低这些疾病导致的发病率。

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