Kato Naoki, Mori Ryousuke, Seki Koujirou, Noda Yasuto, Morooka Satoru, Morita Masayo, Tanaka Toshihide, Abe Toshiaki
Department of Neurosurgery, Fuji City General Hospital.
No Shinkei Geka. 2009 Jan;37(1):51-5.
Cerebral venous thrombosis is an uncommon disease characterized by expansive cerebral edema, venous infarction and massive intracerebral hemorrhage. Magnetic resonance imaging and angiography are useful for diagnosis of cerebral venous thrombosis. A 54-year-old man was admitted with headache, vomiting and right hemiparesis. Computed tomography (CT) revealed subcortical hematoma in the left parietal lobe. Digital subtraction angiography (DSA) demonstrated occlusion of the left Labbé vein with dilation of cortical veins and deep cerebral veins. He also suffered from pulmonary embolization and deep vein thrombosis in the lower extremities. Anticoagulant and thrombolytic agents were administered, then respiratory condition and hemiparesis were improved. However, his condition deteriolated 7 months after the initial attack. CT revealed huge subcortical hematoma in the same site. He underwent craniotomy and intracerebral hematoma was evacuated during treatment with vitamin K. His symptom gradually improved and he was discharged with moderate disability 2 months after operation. Dicision of surgical treatment is difficult because there is a risk of rebleeding due to thrombolytic therapy and progressive venous congestion. Since anticoagulant and thrombolytic therapy are inevitable, surgical indication for refractory intracerebral hemorrhage associated with cerebral venous thrombosis should be considered carefully.
脑静脉血栓形成是一种罕见疾病,其特征为广泛性脑水肿、静脉梗死和大量脑出血。磁共振成像和血管造影对脑静脉血栓形成的诊断有用。一名54岁男性因头痛、呕吐和右侧偏瘫入院。计算机断层扫描(CT)显示左侧顶叶皮质下血肿。数字减影血管造影(DSA)显示左侧Labbe静脉闭塞,皮质静脉和脑深部静脉扩张。他还患有肺栓塞和下肢深静脉血栓形成。给予抗凝和溶栓药物治疗后,呼吸状况和偏瘫有所改善。然而,在初次发作7个月后他的病情恶化。CT显示同一部位有巨大的皮质下血肿。他接受了开颅手术,在使用维生素K治疗期间清除了脑内血肿。术后2个月他的症状逐渐改善,出院时仍有中度残疾。由于溶栓治疗有再出血风险且存在进行性静脉充血,手术治疗的决策很困难。由于抗凝和溶栓治疗不可避免,对于与脑静脉血栓形成相关的难治性脑出血的手术指征应仔细考虑。