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[一例系统性红斑狼疮合并脑梗死和脑出血]

[A case of systemic lupus erythematosus associated with cerebral infarction and cerebral hemorrhage].

作者信息

Hirano A, Miyazaki S, Hashimoto Y, Hashi K

机构信息

Department of Neurosurgery, Hakodate City Hospital, Japan.

出版信息

No To Shinkei. 1995 Oct;47(10):1003-7.

PMID:7577135
Abstract

This is a report of cerebral infarction and cerebral hemorrhage derived from systemic lupus erythematosus. A 49-year-old male was admitted to our hospital due to dysarthria and supranuclear facial palsy. He had been suffering from SLE and medicated incompletely since 9 years prior to admission. A CT scan showed a small infarction in the left parietal area. An angiography revealed a tapering stenosis of the left carotid siphon and an occlusion of the left vertebral artery at the cisternal portion. On the 13 days after the admission, he complained of a high fever and right hemiparesis. The CT scan disclosed newly multiple small infarctions in the left parietal area. The angiography showed the progressing of the tapering stenosis at the left carotid siphon, and demonstrated the narrowing of the left superior temporal artery and ophthalmic artery in addition to the disappearance of a left posterior communicating artery. High dose of steroid was given to him, but cerebral hemorrhage and huge left cerebral infarction were complicated. On the 26 days after the admission, his general condition was worsened and died. It was considered that the cerebral infarction and hemorrhage might be derived from the vasculitis of SLE.

摘要

这是一篇关于系统性红斑狼疮引发脑梗死和脑出血的报告。一名49岁男性因构音障碍和核上性面瘫入院。他自入院前9年起就患有系统性红斑狼疮且治疗不彻底。CT扫描显示左顶叶区域有一个小梗死灶。血管造影显示左颈动脉虹吸部呈逐渐变细的狭窄以及小脑延髓池段左椎动脉闭塞。入院13天后,他出现高热和右侧偏瘫。CT扫描显示左顶叶区域新出现多个小梗死灶。血管造影显示左颈动脉虹吸部逐渐变细的狭窄在进展,除左后交通动脉消失外,还显示左颞上动脉和眼动脉变窄。给他使用了大剂量类固醇,但并发了脑出血和巨大的左脑梗死。入院26天后,他的全身状况恶化并死亡。据认为,脑梗死和脑出血可能源于系统性红斑狼疮的血管炎。

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