Shtemberg A S
Radiats Biol Radioecol. 2008 Nov-Dec;48(6):671-6.
The dynamics of the disturbances of stabilized motor defensive conditioned reflex of active avoidance in "shuttle-box" in rats after total and partial (the head or body irradiated) influence of high energy electrons in dose 100 Gy was investigated. The head irradiation, the same way as total irradiation, provoked the early effects of disturbances of higher nervous activity, specifically, initial shock-like effect--the "early transient incapacitation" (ETI). The head shielding, on the contrary, prevents these disturbances. At the same times the body irradiation in dose 10 Gy (this dose don't provoke ETI effect) provoked practically the same disturbances of higher nervous activity as the total irradiation. Consequently, in animals irradiated in super-lethal doses the early disturbances of higher nervous activity provoked of direct influence of ionizing radiation to the brain. In animals irradiated in lesser doses these disturbances caused of non direct effects basically.
研究了在大鼠“穿梭箱”中，给予100 Gy高能电子全身及局部（头部或身体照射）照射后，主动回避稳定运动防御性条件反射的干扰动态。头部照射与全身照射一样，引发了高级神经活动干扰的早期效应，具体而言，是初始的类似休克效应——“早期短暂失能”（ETI）。相反，头部屏蔽可防止这些干扰。同时，10 Gy剂量的身体照射（该剂量不会引发ETI效应）引发的高级神经活动干扰与全身照射几乎相同。因此，在接受超致死剂量照射的动物中，高级神经活动的早期干扰是由电离辐射对大脑的直接影响引起的。在接受较小剂量照射的动物中，这些干扰基本上是由非直接效应引起的。
