伊马替尼相关的银屑病加重在一名胃肠道间质瘤患者中的管理
Management of imatinib-related exacerbation of psoriasis in a patient with a gastrointestinal stromal tumour.
作者信息
Cheng Haiying, Geist David E, Piperdi May, Virk Renu, Piperdi Bilal
机构信息
Department of Medicine, University of Massachusetts School of Medicine, Worcester, Massachusetts 01655-0002, USA.
出版信息
Australas J Dermatol. 2009 Feb;50(1):41-3. doi: 10.1111/j.1440-0960.2008.00495.x.
A 62-year-old woman with a pre-existing psoriasis was treated with oral imatinib (400 mg/day) for a metastatic gastrointestinal stromal tumour. Within 4 weeks of starting therapy, she developed a guttate psoriasis flare. The eruption markedly improved within 2 weeks following cessation of imatinib. However, it recurred when imatinib was recommenced. She has been able to continue on imatinib (400 mg/day) with low-dose oral methotrexate (12.5 mg/week) controlling the psoriasis.
一名62岁患有银屑病的女性因转移性胃肠道间质瘤接受口服伊马替尼（400毫克/天）治疗。开始治疗后4周内，她出现点滴状银屑病发作。停用伊马替尼后2周内皮疹明显改善。然而，重新开始使用伊马替尼时皮疹复发。她能够继续服用伊马替尼（400毫克/天），同时使用小剂量口服甲氨蝶呤（12.5毫克/周）控制银屑病。
Zotero 插件