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宫颈癌近距离放射治疗:澳大利亚和新西兰当前治疗技术调查

Brachytherapy for cancer of the cervix: an Australian and New Zealand survey of current treatment techniques.

作者信息

van Dyk S, Byram D, Bernshaw D

机构信息

Radiation Therapy Services, Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria.

出版信息

J Med Imaging Radiat Oncol. 2008 Dec;52(6):588-97. doi: 10.1111/j.1440-1673.2008.02025.x.

Abstract

Establishing guidelines for the practice of brachytherapy throughout Australia and New Zealand is one of the goals of the Australasian Brachytherapy Group. To better appreciate Australasian resources and conditions, the group conducted a survey in early 2005. The aims were to survey current practices, to emphasize variations in practice and to determine the availability of advanced imaging and treatment methods to assess resources. A survey was sent to all Australian and New Zealand radiotherapy departments. The survey requested details of treatment with respect to external beam radiotherapy, brachytherapy, optimization methods, reporting methods, scheduling brachytherapy and access to imaging and methods of work-up. Thirty-four departments were contacted with 27 (79%) responses returned. Twenty-one departments use brachytherapy. Doses and fractionation schedules varied and use of sectional imaging was minimal. Individualized dosimetry is practised in a limited fashion by 60% of the surveyed departments. There is high compliance with International Commission on Radiation Units 38 dose reporting recommendations. All brachytherapy units identified have access to CT and 85% to MRI within the hospital settings. Brachytherapy for cancer of the cervix is, currently, largely based on the Manchester system. The survey did emphasize considerable variation in dose and fractionation schemes between departments. The Australasian Brachytherapy Group subgroup intends to proceed with the process of formulating recommendations for cervix brachytherapy. It is intended that these will cover the use of image-based planning and treatment, target definition(s), verification of brachytherapy treatments and a uniform dose-reporting mechanism.

摘要

为澳大利亚和新西兰各地制定近距离放射治疗的实践指南是澳大拉西亚近距离放射治疗小组的目标之一。为了更好地了解澳大拉西亚的资源和条件,该小组在2005年初进行了一项调查。目的是调查当前的实践情况,强调实践中的差异,并确定先进成像和治疗方法的可用性以评估资源。向澳大利亚和新西兰的所有放射治疗部门发送了一份调查问卷。该调查要求提供有关外照射放疗、近距离放射治疗、优化方法、报告方法、近距离放射治疗的安排以及成像和检查方法的治疗细节。联系了34个部门,收到27份(79%)回复。21个部门使用近距离放射治疗。剂量和分割方案各不相同,断层成像的使用很少。60%的被调查部门以有限的方式实施个体化剂量测定。对国际辐射单位委员会的剂量报告建议的依从性很高。所有确定的近距离放射治疗单位在医院环境中都可以使用CT,85%可以使用MRI。目前,宫颈癌的近距离放射治疗主要基于曼彻斯特系统。该调查确实强调了各部门之间在剂量和分割方案上存在相当大的差异。澳大拉西亚近距离放射治疗小组的子组打算继续制定宫颈癌近距离放射治疗建议的过程。这些建议旨在涵盖基于图像的计划和治疗的使用、靶区定义、近距离放射治疗的验证以及统一的剂量报告机制。

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