Comer David M, Edgar J David M
Level 8 Belfast City Hospital, Lisburn Road, Belfast, BT9 7AB, N Ireland, UK.
Cases J. 2009 Jan 29;2(1):99. doi: 10.1186/1757-1626-2-99.
A seventy nine year old lady presented with acute bilateral foot drop and paraesthesia of her lower limbs as a presenting feature of Wegener's Granulomatosis (WG).
There was no evidence of pulmonary involvement and her renal function was normal. WG can masquerade as very diverse pathology. It is recognised that neuropathy can occur early and often in the absence of more classical pulmonary and renal findings, often resulting in a delay in diagnosis.
Anti-neutrophil cytoplasmic antibody (ANCA) testing was particularly useful in this case permitting early diagnosis.
一名79岁女性因韦格纳肉芽肿(WG)的表现,出现急性双侧足下垂及下肢感觉异常。
无肺部受累证据,且其肾功能正常。WG可伪装成多种不同的病理表现。人们认识到,神经病变可早期出现,且常无更典型的肺部和肾脏表现,常导致诊断延迟。
抗中性粒细胞胞浆抗体(ANCA)检测在该病例中对早期诊断尤为有用。