一种由咪唑和L-脯氨酸催化的高效超声促进的Baylis-Hillman加合物的合成方法。

An efficient ultrasound-promoted synthesis of the Baylis-Hillman adducts catalyzed by imidazole and L-proline.

作者信息

Mamaghani Manouchehr, Dastmard Sahar

机构信息

Chemistry Department, Faculty of Sciences, Islamic Azad University, Rasht Branch, Iran.

出版信息

Ultrason Sonochem. 2009 Apr;16(4):445-7. doi: 10.1016/j.ultsonch.2008.12.013. Epub 2009 Jan 4.

DOI:10.1016/j.ultsonch.2008.12.013

PMID:19181559

Abstract

A convenient protocol was developed for the synthesis of the Baylis-Hillman adducts in the presence of weak Lewis base and l-proline at room temperature under ultrasound irradiation. This method provided the products in good to high yields (65-90%) and reasonable reaction times.

摘要

开发了一种简便的方法，用于在室温下超声辐射条件下，在弱路易斯碱和L-脯氨酸存在下合成贝利斯-希尔曼加合物。该方法能以良好至高收率（65-90%）和合理的反应时间得到产物。