Shifflet Allison, Wu George Y
Division of Gastroenterology-Hepatology, Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA.
J Formos Med Assoc. 2009 Jan;108(1):4-12. doi: 10.1016/S0929-6646(09)60026-7.
Non-alcoholic fatty liver disease (NAFLD) includes a broad spectrum of fat-induced liver injury, ranging from mild steatosis to cirrhosis and liver failure. The presence of obesity and insulin resistance is strongly associated with non-alcoholic fatty liver and a greater risk of advanced disease. We present here a review of the mechanisms involved in the pathogenesis of NAFLD, advances in the diagnosis, and options for treatment.
非酒精性脂肪性肝病（NAFLD）包括一系列由脂肪引起的肝损伤，范围从轻度脂肪变性到肝硬化和肝衰竭。肥胖和胰岛素抵抗的存在与非酒精性脂肪肝密切相关，且发生晚期疾病的风险更高。我们在此对NAFLD发病机制、诊断进展及治疗选择方面的相关内容进行综述。
