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Enteric serotonergic neurones ... finally!

作者信息

Gershon Michael D

机构信息

Department of Pathology and Cell Biology, Columbia University, P & S, 630 West 168th Street, New York, NY 10032, USA.

出版信息

J Physiol. 2009 Feb 1;587(3):507. doi: 10.1113/jphysiol.2008.167676.

DOI:10.1113/jphysiol.2008.167676
PMID:19182271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2670073/
Abstract
摘要

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[Regulation of serotonin biosynthesis in the central nervous system].[中枢神经系统中血清素生物合成的调节]
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Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons.肠神经元 5-羟色胺在胃肠动力中的基本作用和肠多巴胺能神经元的发育/存活。
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本文引用的文献

1
Strain-specific genetics, anatomy and function of enteric neural serotonergic pathways in inbred mice.近交系小鼠肠道神经血清素能通路的品系特异性遗传学、解剖学和功能
J Physiol. 2009 Feb 1;587(3):567-86. doi: 10.1113/jphysiol.2008.160416. Epub 2008 Dec 8.
2
Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum.Lrp5通过抑制十二指肠中血清素的合成来控制骨形成。
Cell. 2008 Nov 28;135(5):825-37. doi: 10.1016/j.cell.2008.09.059.
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Serum vasoconstrictor, serotonin; isolation and characterization.血清血管收缩剂,血清素;分离与特性鉴定
J Biol Chem. 1948 Dec;176(3):1243-51.
4
The serotonin signaling system: from basic understanding to drug development for functional GI disorders.5-羟色胺信号系统:从基础认识到功能性胃肠疾病的药物研发
Gastroenterology. 2007 Jan;132(1):397-414. doi: 10.1053/j.gastro.2006.11.002.
5
Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function.非神经元色氨酸羟化酶1(tph1)基因的破坏证明了外周5-羟色胺在心脏功能中的重要性。
Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13525-30. doi: 10.1073/pnas.2233056100. Epub 2003 Nov 3.
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SEROTONIN: SYNTHESIS AND RELEASE FROM THE MYENTERIC PLEXUS OF THE MOUSE INTESTINE.血清素:小鼠肠道肌间神经丛的合成与释放
Science. 1965 Jul 9;149(3680):197-9. doi: 10.1126/science.149.3680.197.
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The action of 5-hydroxytryptamine, 5-hydroxytryptophan and reserpine on intestinal peristalsis in anaesthetized guinea-pigs.5-羟色胺、5-羟色氨酸和利血平对麻醉豚鼠肠道蠕动的作用。
J Physiol. 1959 Apr 23;146(1):29-53. doi: 10.1113/jphysiol.1959.sp006176.
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Synthesis of serotonin by a second tryptophan hydroxylase isoform.第二种色氨酸羟化酶同工型合成5-羟色胺。
Science. 2003 Jan 3;299(5603):76. doi: 10.1126/science.1078197.