利血平和垂体切除对血管及其他组织中胶原蛋白生物合成的抑制作用。
Reduction of collagen biosynthesis in blood vessels and other tissues by reserpine and hypophysectomy.
作者信息
Ooshima A, Fuller G C, Cardinale G J, Spector S, Udenfriend S
出版信息
Proc Natl Acad Sci U S A. 1977 Feb;74(2):777-9. doi: 10.1073/pnas.74.2.777.
Abstract
Synthesis of collagen in the vasculature and other tissues of normotensive rats is markedly reduced by reserpine. Hypophysectomy produces similar effects. The effects of reserpine on collagen biosynthesis may be mediated through the hypothalamus.
摘要
利血平可显著降低正常血压大鼠血管及其他组织中胶原蛋白的合成。垂体切除也会产生类似效果。利血平对胶原蛋白生物合成的作用可能是通过下丘脑介导的。
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