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性功能障碍在病态肥胖男性中很常见,且在胃旁路手术后会有所改善。

Sexual dysfunction is common in the morbidly obese male and improves after gastric bypass surgery.

作者信息

Dallal Ramsey M, Chernoff Arthur, O'Leary Michael P, Smith Jason A, Braverman Justin D, Quebbemann Brian B

机构信息

Department of Surgery, Albert Einstein Healthcare Network, Philadelphia, PA 19027, USA.

出版信息

J Am Coll Surg. 2008 Dec;207(6):859-64. doi: 10.1016/j.jamcollsurg.2008.08.006. Epub 2008 Oct 1.

Abstract

BACKGROUND

There has been limited research examining the mechanisms and epidemiology of sexual dysfunction in the morbidly obese. Our objectives were to measure sexual function in the morbidly obese man before and after substantial weight loss induced by gastric bypass surgery.

STUDY DESIGN

All male patients in undergoing gastric bypass completed the Brief Male Sexual Function Inventory (BSFI) before and after operation. BSFI scores were also compared with published normative controls and analyzed for predictors of change. Mixed models were created to control for age, diabetes, and hypertension.

RESULTS

Ninety-seven men with a mean age of 48 years (range 19 to 75 years) and mean body mass index of 51 kg/m(2) (range 36 to 89 kg/m(2)) underwent gastric bypass surgery. On average, preoperative morbidly obese patients reported a substantially greater degree of sexual dysfunction than did published reference controls in all domains, p < 0.001. Increasing weight independently predicted lower domain scores. Mean postoperative followup length was 19 months (range 6 to 45 months). On average, BSFI scores improved from preoperative levels by bivariate analysis in all categories (means+/-SE): sexual drive (range 0 to 8), 3.9+/-0.3 to 5.3+/-0.3; erectile function (range 0 to 12), 6.4+/-0.5 to 8.9+/-0.5; ejaculatory function (range 0 to 8), 4.9+/-0.4 to 6.3+/-0.4; problem assessment (range 0 to 12), 7.4+/-0.5 to 9.6+/-0.5; and sexual satisfaction (range 0 to 4), 1.6+/-0.2 to 2.3+/-0.2; all p < 0.01. On multivariable analysis, the amount of weight loss independently predicted the degree of improvement in all BSFI domains, p < 0.05. After an average 67% excess weight loss, BSFI scores in postoperative gastric bypass patients approached those of the reference controls.

CONCLUSIONS

Men with morbid obesity commonly suffer from profound, but reversible sexual dysfunction.

摘要

背景

关于病态肥胖患者性功能障碍的机制和流行病学的研究有限。我们的目标是测量胃旁路手术导致显著体重减轻前后病态肥胖男性的性功能。

研究设计

所有接受胃旁路手术的男性患者在手术前后均完成了简短男性性功能量表(BSFI)。BSFI评分还与已发表的正常对照进行比较,并分析变化的预测因素。建立混合模型以控制年龄、糖尿病和高血压。

结果

97名平均年龄为48岁(19至75岁)、平均体重指数为51kg/m²(36至89kg/m²)的男性接受了胃旁路手术。平均而言,术前病态肥胖患者在所有领域报告的性功能障碍程度均比已发表的参考对照严重得多,p<0.001。体重增加独立预测较低的领域得分。术后平均随访时间为19个月(6至45个月)。平均而言,通过双变量分析,所有类别的BSFI评分均较术前水平有所改善(均值±标准误):性欲(范围0至8),从3.9±0.3提高到5.3±0.3;勃起功能(范围0至12),从6.4±0.5提高到8.9±0.5;射精功能(范围0至8),从4.9±0.4提高到6.3±0.4;问题评估(范围0至12),从7.4±0.5提高到9.6±0.5;性满意度(范围0至4),从1.6±0.2提高到2.3±0.2;所有p<0.01。多变量分析显示,体重减轻量独立预测所有BSFI领域的改善程度,p<0.05。在平均减重67%的多余体重后,胃旁路术后患者的BSFI评分接近参考对照。

结论

病态肥胖男性通常患有严重但可逆的性功能障碍。

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