Avian Pathol. 2001 Aug;30(4):423-6. doi: 10.1080/03079450120066421.
The ability of the infectious bronchitis (IB) Ma5 and 4/91 live-attenuated vaccines to protect against kidney damage caused by a nephropathogenic strain of IB virus (B1648) was investigated. Protection parameters considered were gross and microscopic renal pathology, and the use of a polymerase chain reaction to detect IB RNA in kidney tissue. By each parameter, Ma5 vaccine alone provided poor protection, but 4/91 alone or the combined program both protected well.
本研究旨在探讨传染性支气管炎(IB)Ma5 和 4/91 活疫苗对肾致病性 IB 病毒(B1648)引起的肾脏损伤的保护作用。本研究考虑的保护参数包括肾脏大体和显微镜病理,以及使用聚合酶链反应(PCR)检测肾脏组织中的 IB RNA。通过每个参数评估,Ma5 疫苗单独使用时保护效果较差,但 4/91 单独或联合使用时保护效果良好。